|
|
TABLE 5
Drugs That Have Been Associated With Significant Effects on Some
Nursing Infants and Should Be Given to Nursing Mothers With
Caution*
|
| Drug |
Reported Effect |
Reference
No. |
|
| Acebutolol |
Hypotension;
bradycardia; tachypnea |
116 |
| 5-Aminosalicylic
acid |
Diarrhea (1 case) |
117-119 |
| Atenolol |
Cyanosis;
bradycardia |
120-124 |
| Bromocriptine |
Suppresses lactation; may
be hazardous to the mother |
125, 126 |
| Aspirin
(salicylates) |
Metabolic acidosis (1 case) |
127-129
|
| Clemastine |
Drowsiness, irritability, refusal to feed,
high-pitched cry, neck stiffness (1 case) |
130
|
| Ergotamine |
Vomiting, diarrhea, convulsions (doses used in
migraine medications) |
131 |
| Lithium |
One-third to one-half
therapeutic blood concentration in infants |
132-134
|
| Phenindione |
Anticoagulant: increased prothrombin and partial
thromboplastin time in 1 infant; not used in United States |
135
|
| Phenobarbital |
Sedation; infantile spasms after weaning from milk
containing phenobarbital, methemoglobinemia (1 case) |
136-140
|
| Primidone |
Sedation, feeding problems |
136, 137
|
| Sulfasalazine (salicylazosulfapyridine) |
Bloody diarrhea (1 case) |
141 |
|
|
*
Blood concentration in the infant may be of clinical
importance.
|
